Joe Manganiello details secret health battle and brutal side effects

Joe Manganiello said in an Instagram video that he "suffered in silence" while battling a deadly mystery illness he kept hidden for almost a decade. He recalled seeing the best doctors, who could not determine the cause, and said treatments with high-powered biological drugs only exacerbated his symptoms and unlocked a host of brutal side effects.

He described undergoing very serious operations and procedures that "mutilated parts of my body" and left him so weak at times he could not stand or walk. Manganiello also said he spent months heavily medicated while managing excruciating chronic pain. His memoir, Bloodlines, out Oct.

13, documents the ten-year search for answers and explores his family history. A synopsis for Bloodlines says he endured a "cascade of autoimmune-related illnesses" that attacked his thyroid, digestive system, skin, lungs and eyes. Over seven years he faced chronic pain, a life-saving organ amputation, an existential crisis and a prolonged fight for survival that left doctors with few answers.

joe manganiello, bloodlines, memoir, mystery illness, autoimmune disease, chronic pain, biologic drugs, side effects, organ amputation, family history